The course addresses five fundamental mechanisms of human diseases and how to explore them in the laboratory. It provides in-depth analysis of cellular detoxification, cellular bioenergetics, mitochondrial disturbances, malignant transformation and inflammation. The topics are covered in ten seminars. Students need to write a full report on each topic, which composes 50% of the grade. The other aspect of the course includes five laboratory sessions that cover cellular thiols, cellular bioenergetics, intracellular caspases and in vitro assessment of cytotoxicities.
Bioinformatics applies the principles of information science and technology to answer some of today's most complex questions in the life sciences. Its research lies in the development and application of computational approaches for the storage, analysis and interpretation of biological data. In the medical arena, particularly in functional genomics, researchers are currently using technologies that yield vast amounts of complex data. This data first needs to be stored in integrated, highly curated and user friendly databases. Analytical algorithms and analysis pipelines need to be applied to the data in order to extract as much information from the experiment as possible. Finally, in order for the life science community to be able to use these algorithms, they must be packaged in user-friendly, easily accessible tools. Bioinformatics thus has three components: database structure, data mining and data analysis procedures, and software development.
This course is designed to give an overview of hematology and oncology at the level of the third year medical student. The course consists of basic/clinical science lectures combined with relevant laboratory teaching and problem based learning (PBL) in relation with hematologic and oncologic disorders. Students will study basic mechanisms of cancer development, progression, diagnosis, therapy, screening and prevention. They will also study fundamental concepts of hematology including blood-forming organs and the origin and function of blood cells and plasma. They will also examine the theoretical and clinical aspects of normal and pathological conditions of erythrocytes, leukocytes, platelets, coagulation and blood group systems.
In this course, students will be introduced to the basis of human traits with emphasis on genetic disorders and their modes of inheritance. They will also be familiarized with the molecular and cellular basis of genetic conditions and the modalities available for treatment. In addition, they will learn about the genetic disorders that are particularly prevalent in the UAE population and their prevention strategies. Personalised medicines and the concepts of variability to susceptibility and resistance to infections and population genetics will be introduced.
This course aims at developing the principle of genuine inheritance at a molecular level in different living systems from viruses to mammals. This course includes investigation of gene structure and its susceptibility to alteration that results both in benign and malignant outcome, mechanism of recombination and its effect on diversity and amplification of genome, and chromosomal breakage.
During this Course the students will learn about the general mechanisms underlying the alteration of the normal structures and functions of tissues when there is disease and the body’s response. They will appreciate the mechanisms by which the body restores normal structure and function following a disease process. It will also introduce students to basic concepts in neoplasia.
The course is designed to teach the fundamentals of practical laboratory medicine. It will provide the main basics taught in a professional medical laboratory technology course. It will expose students to the workings of a pathology laboratory in a hospital, and could potentially lead to a job in one of the many hospitals in the country.
The course is of General Histopathology which deals with the basic concepts of various disease processes. This program offers the student a comprehensive review of the theoretical and practical aspects of general histopathology. The students will be exposed to formal lectures and laboratory practicals which will emphasize the most modern concepts and methodologies in the fields of cell injury, inflammation, tissue repair, infection, hemodynamic changes, vascular disorders, environmental disorders and neoplasia.
Genetic disorders are a major cause of morbidity and mortality in UAE as well as other populations. Understanding the molecular and cellular basis of these disorders is crucial for the development of effective prevention, diagnosis and treatment. This course will cover the basics and the advanced aspects human genetics.
Molecular Pathology is an emerging discipline within pathology which focuses on the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. It shares some aspects of practice with both anatomic pathology and clinical pathology, molecular biology, biochemistry, proteomics and genetics. Tumor molecular pathology is the branch that encompasses the development of molecular and genetic approaches to the diagnosis and classification of human tumors; the design and validation of predictive biomarkers for treatment response and disease progression, the susceptibility of individuals of different genetic constitution to develop cancer and the environmental and lifestyle factors implicated in carcinogenesis. Molecular genetics pathology deals with basic and translational research aimed at broadening the understanding of gene/protein structure and function, disease processes and molecular diagnostics of genetic conditions.
This program offers the students a comprehensive review of the theoretical and practical aspects of Hematology. The students will be exposed to formal lectures and laboratory practicals which will emphasize the most modern concepts and methodologies in the fields of hematopoietic, lymphopoietic and hemostatic disorders (see course contents). The course will include sections in which the students will receive instruction in the physiopathologic mechanisms, diagnosis and therapy of the different types of anemias, leukemias, lymphomas and hemorrhagic/thrombotic disorders. In addition, a section dedicated to immunohematology in which the students will extensively learn current theoretical concepts and practice of blood transfusion will also be included. In that regard the students will also be taught present infectious disease donor screening programs essential to the practice of safe blood and blood component therapy.
This course is designed to familiarize postgraduate PharmD students with the concepts of clinical chemistry, hematology and translate them into laboratory work and apply it to patient care. The course will focus on the basics of clinical chemistry, hematology and clinical laboratory methods. It will emphasize the importance of laboratories in the work-up of patients for diagnosis, follow-up and screening of disease. The seminars are structured and followed-up by practical case analysis in hospital laboratories to help in understanding the theory and practice of laboratory medicine. This course will be in a seminar fonnat as well as group discussions and laboratory based cases.
This course will discuss the topics of water and mineral balance and excretion.