312
3961965989012055111
Profiles3670599101205989154179203223288327
of4025599101206596
Doctorate41495991012075140205239304334403436501
Dissertations4678599101207595133172237267301369403423489550589
Research1493848013464134183253326361431497
Relevance2021848013464134161231293365431502572
and2624848013472138211
Potential2866848013461132165235301334361433460
Impact3356848013431135207280350383
Diabetes1493106401466891143198251284337382
is1906106401464084
a20221064014669
serious21221064014662114150173228283328
health24811064014673126178201234290
problem28021064014672108163218241294378
throughout32111064014650106142196252307363417473507
the37491064014650106158
world.39391064014691145181204259290
5.1%42601064014671102156254
of45451064014671103
the46791064014651106159
world48691064014691146182205260
populations51601064014672127182238261313346369424479524
(20057151064014655110164219
millions)14931274014684107130153176230286330369
suffer1893127401464096127159212248
from2172127401462864118202
diabetes.2401127401465578131186239272325369400
This28271274014659115138182
number30361274014656112196251304340
is3407127401461863
expected3501127401464898153206252285338393
to3926127401462983
increase4040127401461975121157209262307359
up44261274014656111
to4569127401462983
33546791274014654109164
million48701274014684106129152175229285
in5187127401461874
2025.52871274014655110164219249
Around5621127401465692146202258313
28%14931484014655109207
of1731148401466698
the18601484014645101154
total2045148401464599133185208
population22841484014667122177233256308341364419474
in2790148401463490
the29111484014645101154
Gulf30961484014678134157189
countries33161484014658112168224257293316368413
are37601484014665101153
diabetes.3944148401466790143198251284337381412
Recent44301484014674126172225281314
results47751484014648101145201224257302
on51081484014666122
the52611484014645101154
prevalence54461484014667103156205258281333389435488
of1493169401465486
diabetes1610169401466588140196248282334379
in2020169401463288
the2139169401464399151
UAE23221694014675135191
have25441694014665118167220
indicated2795169401463288143166212265298351406
that3233169401464298150184
about34481694014662117172227261
24-3037401694014664118155209264
%40441694014698
of4173169401466496
the4300169401464399151
population44821694014665119175230253306339362416472
suffer49861694014653109141173225261
from5279169401464177131215
diabetes.5525169401466588140196248282334379409
Elevated1493190401465679132181234267320375
blood1899190401465578133187242
glucose2172190401465578134180234279331
levels2535190401462275125177200245
in2811190401462278
diabetic2920190401465578131186238272295341
patients32921904014655107141164216272306350
may36731904014684137186
impact38911904014622106161214260293
all421619040146527497
systems4345190401464494138172224308353
in4729190401462378
their4839190401463288141164200
body.50701904014655109165214245
It5346190401463770
can5447190401464699154
lead5633190401462275127182
to5847190401463387
many14932114014684136192242
complications,17662114014654108192248271294340392425448503558603633
such24312114014652108154210
as26722114014660105
neuropathy,28082114014664116172208262318370404459509540
increased3379211401463086132168221273318371426
blood3836211401466386141195250
pressure,4117211401466399152197241297333386416
cardiac45642114014654107143198221273319
problems,4915211401466399153208231284368413443
deteriorated53892114014663116149202238261315351403437489545
vision1493232401465073117140194250
and17752324014668124179
even19862324014668118171227
blindness2244232401467294117173228284337381426
and27012324014669125180
circulatory2912232401466386122168223246299332387423472
disturbances.3416232401467194139172228264319372428474526571601
Therefore40482324014675131184220272304358394447
diabetes4526232401467295147203255289341386
constitutes49432324014662117173217251273307363396449493
a54682324014668
national55682324014672124158181235291343366
health14932534014656108161184217273
concern17972534014663118173219272308364
in2192253401464096
the23192534014650106159
UAE25092534014683143199
and27392534014670125181
internationally2951253401464095129181217273326359382436492545568590640
and36232534014669125180
still3834253401466295118141164
intensive4029253401464096129182237282305355407
research44682534014653105150202255291337393
efforts48922534014670102133188224257302
are52252534014670106158
required54152534014653105160216239275328383
to58292534014651105
combat14932744014646100184240292326
the1850274401463389142
disease.2023274401465578123175228272325355
Although1493302401466083116172226282338393
insulin19173024014648104148204227250306
is2254302401464792
the23773024014658114166
essential25753024014677122166219275308331384406
medicine301330240146108161216239285308364416
currently34613024014670126162198251307340363413
used39053024014680125178233
in41693024014648103
the43043024014658113166
treatment4501302401465894147199233317369425459
diabetes,49913024014680103155211263297349394424
it5446302401464881
has55593024014680133177
the57673024014658114167
disadvantages1493323401465578123175231280333389422475530582627
of2140323401465486
being22463234014656108131187242
expensive,25083234014653102158210266311334383436466
unstable29943234014656112157190242298321373
at3387323401465386
room3504323401462580134218
temperature3753323401462275159214267303355389445481533
and43063234014653109164
patients44903234014655108141164217273306351
have48613234014655108158210
to5103323401462276
be51993234014656108
subcutaneous53273234014645101156202258291344400452506562607
injected1493344401462379107159206239292347
several18713444014651103153206242294317
times2219344401464063147199244
every24943444014658108161197247
day.27723444014661114163194
Moreover,30033444014677131167220274324377412443
type3477344401463989144197
237053444014661
diabetic3797344401466184137192245278301347
patients41753444014661114147170223279312357
are4563344401465894147
subjected47413444014651106162190242289322375430
to5202344401463994
hypoglycemia53273444014662112167221276299349395448532555607
and14933654014652108164
gain16883654014657109132188
in1907365401462580
weight20203654014675127150205261295
Therefore,23463654014660116168204257289343379432462
oral2839365401465692145168
hypoglycemic30383654014657107162217272295345391443527550596
drugs3666365401465793148204248
can39463654014647100156
be41333654014657109
considered42743654014647102158202225280333369422477
good47823654014657111166221
alternative5034365401465477111163199255308341364414466
remedies5532365401463790174227282305357402
used14933864014656100153208
for1733386401464297133
treating1897386401464480133185219242298353
diabetes.2281386401466689142197250283336380411
To27233864014669124
date,28783864014666119152205235
pyrimidine31443864014667116152175259282337360416469
analogues36443864014663119172195249304360413457
(PTZ)41323864014650105163219257
have44213864014666119169221
not46743864014666121154
thoroughly48593864014645100155191245301356412435485
evaluated53753864014663113166189244297330383438
in5844386401463490
relation1493407401463689111164197220275330
to1855407401463387
exploring19744074014652102157180234270293349404
their2410407401463389141164200
potential26424074014655109143195251284307360383
to3056407401463388
act3175407401465299132
as3338407401465397
ant-diabetic34674074014652108141178233256308364416450473519
drugs.4017407401465591147202247277
Increased1493435401463793139175228280325378433
interest1957435401461874108160196249293327
in2315435401461974
new24164354014656108182
oral2625435401465490143166
hypoglycemic28184354014655105160215270293343389441525548594
therapies3444435401462884137173225281303356401
is3876435401461863
widely3965435401467598153205228278
demanded42704354014655108192244300355408463
all476543540146477093
over48854354014654104156192
the5109435401462884137
world.52734354014674128164187242273
A55724354014660
library566343540146194197133185221271
of1493456401465486
new16104564014662115189
molecules18374564014684138161214260316338391436
with23044564014680103137192
potential25284564014661116149202257291314366389
anti-diabetic29484564014659115148171207263286338393446479502548
activity35284564014658104138161211233267317
designed38764564014662114159182237293345401
and43084564014659114170
synthesized45094564014651101156190246298343366410463518
and50584564014659115170
their5259456401464096148171207
structureactivity54984564014650841201762222553113474001493477401465299132155205228261311
relationship18354774014660113135188221244299354399455478533
(SAR)23994774014662118178240278
investigated27094774014646102152204249282305361413447499554
in32954774014646102
this34294774014657112135180
project.36404774014679115170198250297330360
Their40324774014682138190213249
pharmacokinetics43124774014680135188224308360406461511533589642675698744789
and51324774014676132188
physiological53514774014679135184229252306329383439462508560583
effects1493498401465384116169215248293
on18174984014662118
diabetic1966498401466386138194246279302348
animals23464984014660116138222275298342
will27204984014681104127150
be29014984014663115
studied.3048498401465285141196219272327357
Successfully34374984014663118164211263308352384440463486536
active40044984014660106139162212265
compounds43004984014653108192247301357413468513
can48444984014654106162
proceed5037498401466399153199252304360
to5428498401464195
the5555498401464096149
next57354984014663116165199
phase14935194014655111164208261
as17855194014655100
possible19165194014658113157202225280303355
patent23035194014658110144196252285
anti-diabetic26205194014655111144167203259282334389442475498544
agents.31965194014655110163219252297327
Such35545194014659114161216
promising3802519401465894148232255299322378433
therapeutic4267519401463691144180233288340396430453499
agents47975194014655111163219252297
could51255194014649103159182237
be53945194014658110
the5536519401463691144
basis57115194014658111156178223
for1493540401463286122
novel16465404014658113162215238
anti-diabetic19155404014655111144167203259282334389442475498544
drugs2491540401465793149204249
developed27715404014657110160212235290345398453
in3255540401462581
UAE.33675404014668128184214
This36135404014660116139183
project3828540401465793147176228274308
will4169540401467497120143
give4343540401465881131183
a45575404014655
chance46435404014649104157213259311
for4986540401463488124
UAEU51415404014668128184250
researchers5422540401463891135188241277323378431467512
to1493561401463388
participate16125614014673125161195217264286342394428480
in2124561401464096
an22515614014670125
international2408561401464096129182218273326359382436492545568
scientifically30075614014662108131183239273295322349395447470493543
and35815614014670126181
economically37935614014670116171226281365388434486509532582
important44065614014640124179234270303356411445
area48825614014670106159211
of51245614014672104
research,52595614014653106151203256292338394424
drug57145614014673109165220