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The aim of this course is to introduce basic biochemical laboratory techniques, with emphasis on protein biochemistry. The students will learn to use standard biochemistry lab instruments such as pH meters, spectrophotometers, pipettes, microplate readers. Standard protein purification and characterization techniques, enzyme activity assays, as well as immunoassays (ELISA) will also be taught.
The aim of this course is to apply the basic knowledge gained in Biochemistry (CHEM 361) course to specific metabolic reactions and certain physiologically important biomolecules. The course covers bioenergetics, photosynthesis, regulation of carbohydrate metabolism, biosynthesis of glycoproteins, mechanisms of transport through membranes, immunoglobulins and immunity, blood clotting proteins, and biochemical communications.
The aim of this course is to study three principal aspects of proteins - physical properties, interaction with other biomolecules, and biochemical function - with an emphasis on levels of protein structure, folding conformation, biosynthesis, ribosome assembly, targeting, protein degradation, protein/DNA interactions and gene expression, membrane proteins and receptors, signal transduction, muscle action proteins.
This course aims to cover selected topics dealing with the recent advances in the field of genomics (genes related issues) and proteomics (protein related issues). The course will also discuss the current knowledge on cellular signal transduction, and link it with the actions of hormones, clinical biochemistry, as well as some types of cancer. Special attention will be paid to nuclear hormone receptor and G-protein coupled receptor signaling pathways. Students will be required to read up on primary literature and make an oral presentation to the whole class on a chosen topic.
This course aims to cover selected topics that are not discussed in other courses that of current importance such as effects of environmental pollutant on biochemical metabolism, drug and antibiotic metabolism, antibodies and immunochemistry, biotransformation and detoxification.
Matter and measurement. Atoms, molecules and ions. Chemical stoichiometry. Acids-Bases and oxidation-reduction reactions. Oxidation numbers and the balancing of equations. The electronic structure of atoms and the periodic table of elements. Periodic properties of the elements. Basic concepts of chemical bonding and molecular geometry. Gases. Intermolecular forces. Solubility and Concentration units.
Thermochemistry. Reactions in aqueous solutions. Gaseous equilibrium. Acids and bases. Ionic equilibria. Qualitative analysis. Electrochemistry. Rates of reactions.
Introduction to the elementary laboratory techniques. It includes principles of chemical calculations, techniques of qualitative analysis with special emphasis on applications of chemical equilibria.
Chemistry Lab 1 for Engineering is an introduction to elementary laboratory techniques. It includes the principles of chemistry calculations, techniques of quantitative and qualitative analysis.
The role of chemistry in important issues of modern life is examined including the economic, social, health and ecological impact of chemistry. Chemical concepts are presented through examining various topics such as environment, ecology, nutrition and health.
The aim of this course is to provide chemistry students with a wide range of generic, transferable skills, essential in and beyond the chemistry profession and to prepare students adequately for the Internship program and later professionally in the work-place. The course involves several different chemistry-specific components, including general study skills, communication skills both written and oral, critical-thinking exercises, group and project work, project management, time management and chemical information retrieval. Students are also given hands-on experience in tailored IT packages for chemistry, chemistry-specific computational programs, including chemical structure modeling etc. The module is delivered by Chemistry faculty through a combination of interactive active learning workshops, group work, presentations and hands-on sessions in the computer laboratory.
This course deals primarily with non-instrumental techniques in quantitative chemical analysis. The topics covered include volumetric and gravimetric methods which based on solution equilibria such as acid-base, complexometric, redox and gravimetric reactions. The course also aims to introduce students to the various types of errors in chemical analysis, kinetic methods of analysis and non-chromatographic separation methods. The associated laboratory experiments provide experience in applying these methods in chemical determinations.
This course involves topics in basic inorganic chemistry which cover the structure and bonding in molecules, the chemistry of the oxoanions and oxoacids, solvents, solutions, acids and bases and the chemistry of selected main group elements and their associated compounds. The course covers the following areas explicitly: the structure of atoms, atomic orbitals in wave mechanics; periodic properties of the elements; structure and bonding in molecules: introduction, molecular orbital theory: homo and heteronuclear diatomics, polyatomics, multicentre MO, electron-deficient molecules, ?-donor and acceptor ligands; elements of symmetry, symmetry operations and point group symmetry determination; ionic solids: lattice and close-packing concepts, ionic radii, lattice energy calculations and correlation to properties solubility, hardness etc.; metallic substances: metallic bonding, band theory, conductivity, semiconductors, insulators, defects, preparation of new materials through doping, metallurgy; solvents, solutions, acids and bases; chemistry of the main-group elements.
Introduction to organic chemistry. Nomenclature, isomerism, sources, methods of preparation, physical properties, reactions and mechanisms of: alkanes, alkenes, alkynes, alicyclic hydrocarbons, alkyl halides, alcohols and ethers. Stereochemistry and optical activity. IR and UV-Vis spectroscopy.
Nomenclature, methods of preparation. Physical properties. Reactions and mechanisms of the following organic compounds: aldehydes, ketones, carboxylic acids, esters, amides, anhydrides and other acid derivatives and aromatic compounds. Introduction to carbohydrates, proteins and lipids. Introduction to NMR spectroscopy and mass spectrometry.
Characterization of some organic compounds using physical and spectroscopic techniques, study of the chemical properties of some aliphatic and aromatic compounds containing functional groups.
The First law of thermodynamics. Thermo-chemistry, Second law of thermodynamics. Entropy and free energy. Third law of thermodynamics. Absolute zero. Chemical potential. Phase equilibria. Statistical thermodynamics.
Types of bonding, hybridization of carbon. Naming, preparation in the laboratory and on an industrial scale, applications, chemical and physical properties of organic compounds: Aliphatic and aromatic hydrocarbons, alkyl halides, alcohols, thio alcohols, phenols, ethers, sulfides, aldehydes, ketones, carboxylic acids and derivatives, amines, polymers, structure/physical property relationships in organic chemistry.
The first law of thermodynamics. Thermochemistry. Second law of thermo-dynamics. Entropy. Free energy. Third law of thermodynamics. Absolute zero. Phase equilibria. Solutions. Chemical Equilibria. Electrochemistry. Attention will be focused on the underlying engineering applications.
This course aims at studying basic concepts and fundamentals of material science and engineering in order to develop the understanding that how structure, properties, and processing relationships are established and used for different types of materials. Topics covered are bonding, internal micro-and macro structure, crystallography, material defect; mechanical, thermal, electrical, magnetic, and optical properties of materials; strengthening mechanisms and failure analysis; micro-structural deign of materials.
This course covers both classical and instrumental methods of chemical analysis. Titrimetric methods based on acid-base reactions, complex formation, precipitation, oxidation-reduction reactions are covered. Instrumental methods include spectrochemical, electrochemical and chromatographic techniques. The practical component includes experiments related to the above topics.
Introduction to structure. Nomenclature. Physical properties. Preparation, reactions of hydrocarbons and functional groups containing organic compounds. The laboratory component includes the purification, isolation, characterization and study of the properties of typical organic compounds.
The chemical and physical properties of biological compounds. Theories of enzyme action and the factors affecting them. The practical component includes the isolation and study of biological properties of some biological compounds.
This course aims primarily at developing the fundamental understanding of theory and applications of instrumental analytical techniques. The topics covered include spectrochemical, electrochemical and chromatographic techniques. The associated laboratory practical component provides extensive experience in applying these techniques to the chemical analysis of different samples.
This course introduces the basic principles of coordination chemistry involving the following areas: introduction, chemical nomenclature, stereochemistry and isomerism of coordination compounds; theories of bonding in coordination compounds; the Jahn-Teller Effect; magnetic properties of transition metal complexes; electronic spectroscopy, term symbols and the spectrochemical series; thermodynamic aspects: formation constants, hydration enthalpies, ligand field stabilization energies, chelate effects; tautomerism, stereochemical nonrigidity and fluxionality; synthesis and types of reactions of complexes; lanthanides and actinides; mechanisms of inorganic reactions.
This practical course covers the preparation and identification of a variety of main group and transition metallic compounds. The experiments include important inorganic synthetic techniques and methods of spectroscopic characterization.
This experimental course covers multiple step syntheses of selected organic compounds and the characterization of their functional groups by spectroscopic analysis.
This course covers two areas of physical chemistry, namely kinetics and quantum mechanics. The first part deals with chemical kinetics and the topics include the study of rate of chemical reactions and of the molecular processes by which the reaction occurs, differential and integral expressions with emphasis on multi-step as well as single-step first-order phenomena, expressing mechanisms in rate laws, consecutive elementary reactions, steady state approximation, reactions approaching equilibrium, collision theory, complex reactions, catalysis, photochemical reactions, molecular reaction dynamics, and diffusion controlled reactions. The second part deals quantum mechanics and the topics included are fundamental principles of quantum theory, such as Schrodinger equation, wave functions, quantum mechanical operators, quantum mechanics of a particle-in-a-box model.
The main objective of this course is to provide students with the necessary training on the use of modern techniques and instrumentation in thermodynamics, electrochemistry, kinetics and surface chemistry.
This course involves experimental and computational techniques in physical chemistry. The course contents include: infrared and visible-ultraviolet spectroscopic experiments for chemical analysis, identification of molecular structure, determination of molecular geometry, and chemical kinetics; molecular modeling and simulations; computational chemistry, which includes quantum mechanical and semi-empirical methods.
Structure and chemical behavior of biochemical compounds, levels of protein structure, steady state enzyme kinetics and activities, fatty acid metabolism and lipoproteins utilization, phospholipids and membrane assembly, nucleotides and nucleic acids, amino acid metabolism, carbohydrate metabolism and intermediary regulation, bioenergetics and oxidative phosphorylation. The experimental component provides students with a range of techniques and methodology including sequential configuration, chromatography and electrophoresis for the isolation, separation and characterization of biomolecules; protein determination and enzyme activity assays.
The course deals with the fundamental concepts and applications of instrumental techniques in chemical analysis. The course covers some spectroscopic, electroanalytical, thermal, mass spectrometric and chromatographic methods of analysis.
This course involves students getting some exposure to selected advanced chemical laboratory techniques across all domains of chemistry, involving a problem-based learning approach.
In this course, a student carries out a short research project under the academic supervision of a faculty member in the Department. The aim of the course is to provide students with an opportunity after a successful review of the chemical literature to apply their chemical knowledge and skills to an area of research without the restrictions of a planned practical. The student is expected to devote a set number of hours per week to research as discussed with his or her academic supervisor. At the end of the project, the student must submit a report on his/her research results, present a poster and give a short oral presentation based on the work.
The student spends 8 weeks of training in an approved training site. (This course is conducted over half a semester (8 weeks) during the third year of study. Offered condensed courses should be taken during the other half of the semester).
This theoretical course aims to introduce students to the general principles, basic instrumental aspects, and analytical applications of mass spectrometry, infra red spectroscopy, nuclear magnetic resonance spectroscopy, atomic X-ray and hyphenated techniques.
This course covers the descriptive chemistry of main-group and transition metal elements and compounds synthesis, structures, properties, acid-base character, reactivities etc.. The course will cover selected main-group chemistry from the Periodic Table of Elements and selected elements and their associated complexes from the first-row transition metal d-block elements.
This practical course is designed to equip the student with basic strategies and techniques for the elucidation of molecular structure. It takes the students through a number of modern spectroscopic techniques mass spectrometry and infrared spectroscopy, nuclear magnetic resonance and ultraviolet/visible spectroscopy for the identification and quantification of chemical compounds. The emphasis is on practical applications. The course teaches the student what specific information can be obtained by each technique, proper sample preparation, proper instrumental use and interpretation of spectra. On successful completion of this course, the student will be able to select the most suitable spectroscopic methods to logically deduce the structures of unknown molecules.
This course is a continuation of CHEM 351. It introduces quantum mechanical treatment of the harmonic oscillator and the rigid rotor models, quantum angular momentum, the hydrogen atom, multi-electron atoms, chemical bonding, and molecular orbital theory.
The course is intended to cover the principles of electrochemistry and its applications; topics such as ionic interaction, conducting properties of electrolytes, interfacial phenomena and double layer, thermodynamics and kinetics of electrochemical reactions and electrode processes and applications will be studied.
Advanced treatment of spectroscopic techniques and instrumentation. Atomic and molecular absorption, emission, and scattering processes and their application to quantitative chemical analysis are outlined.
Theoretical and practical aspects of gas and high performance liquid chromatographic methods; supercritical fluid chromatography and capillary electrophoresis. Related instrumentation and selected applications are discussed.
Review of the relevant thermodynamic, kinetic, and electronic principles of electrochemical techniques used for analysis and for the characterization of inorganic and organic systems.
Electronics as applied to chemical instrumentation; design and construction of instruments used in chemical research, analysis, recording, and control
The course is an intensive integrated course of study to introduce students to advanced concepts, reactions, and techniques in contemporary organic chemistry. Focus on multi-step synthesis of diverse target molecules.
A mechanistic view of free-radical reactions, polar reactions, dipolar reactions, pericyclic reactions, frontier molecular orbital theory.
The course deals with basic catalysis, metal-mediated reactions, enzyme catalysis and organocatalysis. Applications of transition metal organometallic compounds in catalysis and organic synthesis will also be discussed.
An introduction to the chemistry of polymers, including synthetic methods, mechanisms and kinetics of macromolecule formation, and polymer characterization techniques.
The course will build on the basics of biochemistry the students should already be familiar with and cover in detail various biochemical topics that are of current interest. Specifically the course will be comprised of three separate modules – advanced protein structure and function (including protein purification & enzymology), metabolism of pollutants (including oxidative stress and reactive oxygen species), and cellular signaling. The students will also be exposed to primary literature in the above mentioned areas of biochemistry and they will be asked to make a class presentation reviewing, presenting, and critiquing a published paper on environmental toxicology.
A study of the evolution, structure, dynamics, stability, folding and degradation of proteins as well as the relationships between primary, secondary, tertiary and quaternary structure and catalytic properties of enzymes. The student will explore the relationship between conformation and energy change and the enzyme kinetics and mechanisms of catalysis.
Amino acid, nucleotide, carbohydrate and lipid metabolism with focus on regulation; allosteric regulation and its relevance to enzyme mechanism and metabolic function; and/or genetic regulation of an enzyme or group of enzymes in a related pathway.
Advanced course in inorganic chemistry focusing on one of the following topics: Transition metal organometallic chemistry, bioinorganic chemistry, inorganic cluster chemistry, solid state inorganic chemistry.
Develops foundation of basic surface science concepts and techniques. These concepts include structure of clean and adsorbate covered surfaces, chemical bonding of adsorbates, energy transfer mechanisms on surfaces, and catalyzed surface reactions.
Develops foundations for application of elementary group theory to organize or simplify problems in quantum chemistry. Applications include molecular orbitals, molecular vibrations, and ligand field environments.
Advanced course in physical chemistry focusing on one of the following topics: Chemical Thermodynamics, Statistical Thermodynamics, Molecular Spectroscopy, Chemical Dynamics, Quantum Chemistry, Materials Surface Characterization
Ideal and non ideal systems, State functions and their relationships with molecular systems, Ensembles, Partition functions of molecules, Application of Fermi Dirac and Bose Einstein statistics
Molecular energy levels, Spectroscopic selection rules, Applications in rotational, vibrational and electronic spectra of molecules, Chemical bonding
A mechanistic view of free-radical reactions, polar reactions, dipolar reactions, pericyclic reactions, frontier molecular orbital theory.
Chemistry of polymers, including synthetic methods, mechanisms and kinetics of macromolecule formation, and polymer characterization techniques.
Elucidation of molecular structure utilizing IR, UV, and NMR spectroscopy, mass spectrometry, and other methods.
This course will investigate how the exploitation of biological systems has been used to manufacture biological and medical products. The course will begin with the history of the biotechnology industry and move to the most common technologies employed and finish by discussing the regulation of the industry and its products. Topics will include therapeutic (proteins, antibodies, retroviruses, etc.) as well as diagnostic (ELISAs, Enzymatic assays, etc.) products that have been developed and are in the pipeline.
This course investigates signaling systems, which allow inputs from outside of a cell, such as growth factors and hormones to regulate cellular behavior. The student will study the mechanisms by which activation of intracellular and cell surface receptors control cell metabolism, motility, proliferation, survival and how different classes of molecules exert their actions. The course emphasizes a mechanistic understanding of how signaling proteins are regulated, a historical view of how signaling pathways were elucidated, and an investigation of the tools used to study signal transduction. Topics will also include the role of (aberrant) cell signaling in cancer biology.
This course studies subjects related to synthesis, structure, properties, and applications of solid materials. The topics that are discussed in this course include, structure and bonding in solids, crystals and crystalline solids, preparative methods, characterization, and physical properties of solids. The course also discusses selected solid materials and their applications, with special emphasis on nano-materials in advanced applications such as electronics and catalysis.
Chemistry of monomers, oligomers and polymers. Polymerization mechanisms, processes synthesis and polymerization kinetics; structure of glassy, crystalline, and rubbery polymers. Emulsion, suspension , bulk and solution polymerizations. Structure of amorphous and crystalline polymeric materials Techniques for polymer characterization and analysis.
The course will cover the methods used for surface and interface analyses and characterizing their properties, composition and structure. Techniques based on interactions of light beams, electron beams and ion beams with matter will be reviewed in terms of its theoretical background, components, applications as well as limitations and advantages. Samples’ preparation for each technique and examples of problem solving in different fields using surface analysis will be provided.
This course aims to introduce students to the general principles, basic aspects, and analytical applications of molecular mass spectrometry. It will discuss the different ionization methodologies and sample introduction methods. Different types of mass analyzers will be introduced where the advantages and limitations of each type will be pointed out. Vacuum and detection systems will be presented. Hyphenated systems such as gas chromatography mass spectrometry (GC-MS) and Liquid chromatography mass spectrometry (LC-MS) will be discussed. Tandem mass spectrometry (MS/MS) and fragmentation mechanisms of organic compounds will be introduced as tools for structure elucidation. Applications of mass spectrometry in analyses of different samples will be discussed.
Fundamentals of polymerization reaction mechanisms and kinetics for step growth, chain growth, free radical, anionic, cationic, metathesis and ring opening polymerizations. Treatment metal, Ziegler-Natta, and Metalloncene chemistry. Chemistry of living anionic, cationic and free radical polymerizations. Co-polymers and reactivity ratios. Block and graft copolymerization. Stereochemical and tacticity in polymers. Polymerization reaction in batch, continuous stirred tank reactor (CSTR) and tubular reactor.
An interdisciplinary investigation of matter at the nanoscale, heterogeneous catalysis, nanoencapsulation, colloidal chemistry, physical characterization of nanoparticles and quantum dots.
Experimental and theoretical aspects of chemical reactions induced by visible and Ultraviolet radiation. Fluorescence and chemiluminescence.
This course investigates transition metal organometallic chemistry in depth. Although, the main focus of the course is organometallics of transition metals, it starts with an introduction on main group as well as transition metal organometallic compounds. The course then investigates, in relation to transition metal organometallics, the following topics: structure and bonding, ligands, synthesis, reactions, structure-reactivity relationships, and applications of organometallic complexes in organic synthesis and industrial catalysis.
This course aims to introduce graduate students to the area of chemical sensors and biosensors. Topics to be covered include: structure and properties of various recognition materials and reagents; physicochemical basis of various transduction methods; auxiliary materials used in the constructions of chemical sensors and biosensors; advanced manufacturing methods; and versatility of sensors’ constructions. Selected applications of some electrochemical, optical, mass and thermometric sensors in biomedical, industrial and environmental fields are to be discussed
Includes chemical reaction dynamics, electrochemistry and interface kinetics, advanced corrosion and inhibition theories and mechanisms, modern nuclear and radiation chemistry, atmospheric chemistry.
Theory and mechanisms of corrosion, thermodynamics, kinetics of corrosion. Passivity; Pourbaix diagrams; corrosion rate testing and measurements; forms of corrosion; effects of alloy and environmental variables; corrosion testing. Wear mechanisms: adhesive, abrasive, erosive. Fretting; surface roughness, wear testing. Coatings for corrosion and wear protection. Effect of mechanical stress on corrosion, examination of various topics in the area of electromechanical and corrosion science, corrosion testing.
Properties and synthetic routes of important industrial polymers (LDPE, HDPE, LLDE, etc.). Economic and chemical development and feeds tocks. Rubber elasticity, polymer, morphology and molecular orientation. Glass transition temperature. Liquid crystalline polymers. Blend and alloys. High-temperature polymers; Thermal stability, degradation mechanism. Viscoelastic behavior of elastomers and plastics. Reaction injection molding and resin transfer molding.
Chemical composition of living matter and the chemistry of life processes. Characterization of amino acids, proteins, carbohydrates and lipids; enzymology and co-enzymes; metabolism of carbohydrates; biological oxidations. Metabolism of lipids, amino acids, and nucleotides; membrane biochemistry; biosynthesis of DNA, RNA, and proteins; gene regulation.
Advanced course in inorganic chemistry focusing on one of the following topics: Chemical Applications of Group Theory, Chemistry of f-block elements, Identification and Characterization of Inorganic Compounds, Nanoscale Materials.
Advanced course in physical chemistry focusing on one of the following topics: Chemical Bonding and Spectra, Nuclear and Radiation Chemistry, Heterogeneous Catalysis and Colloid Chemistry.
Manufacturing processes and refinery. Separation processes. Polymerization and alkylation processes. Oil products and coke. Pollution problems and control. Safe storage. Transport and handing.
Presentation of contemporary concepts on the biochemistry of toxins and pollutants. Destructive action of toxins on biological cycles of living species. Biochemical mode of action of insecticides.
Application of chemical principles and techniques to specific environmental problems and chemical interrelationship among these problems. Air and water pollution. Organic and inorganic pollutants. Tools of removal and recovery of pollutants. New methods of environmental detection and sampling.
Theory and practice of the relevant corrosion processes to specific environmental problems. Corrosion in reinforced concrete, pipelines, power plants.... etc. Selection of construction materials. Corrosion control and continuous monitoring for health and safety.
This course will introduce students to the advances in methods used for chemical analysis of different substances. The course will cover advances in spectroscopic, electro analytical and/or chromatographic techniques. Applications related to analyses of chemical, biological and environmental samples will be considered
The course is an intensive integrated course of study to introduce students to advanced concepts, reactions, and techniques in contemporary organic chemistry. Focus on multi-step synthesis of diverse target molecules.
This course analyzes protein structure function relationships. Students will investigate how a proteins sequence gives rise to structure and how the structure then relates to function. Topics in evolution, domains, motifs, stability, folding and degradation of proteins as well as relationships between structure and catalytic properties of enzymes will be discussed. Students will read and discuss the current scientific literature and use modern visualization tools to investigate structure/function.
This course describes modern theories of chemical bonding and their application in the prediction and interpretation of molecular properties. Topics include applications of group theory, valence bond theory, and molecular orbital theory in the study of structure, reactivity, electronic spectra, vibrational spectra and electrochemical properties of main group and transition metal compounds.
Includes classical and statistical thermodynamics, chemical kinetics, advanced molecular quantum mechanics and spectroscopy, elements of computational chemistry.
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