This course covers normal and abnormal processes in the cardiovascular system and introduces clinical approaches to diagnosis and treatment of the most prevalent cardiovascular diseases.
This course covers basic pharmacology topics such as the nature of drugs, the different forms of drugs, the processes and the factors that influence their absorption, transportation, effectiveness, and elimination. Students will be able to relate the normal and abnormal processes of the autonomic nervous system and the pharmacological agents which forms the bases for the therapy for the autonomic system disorders.
This course is designed to teach graduate students the effects of drugs on different organ systems. The drugs acting on major organ systems will be reviewed (the autonomic nervous system and the cardio-vascular, respiratory, kidney, endocrine, gastrointestinal, neuromuscular transmision, antimicrobials and central nervous systems). The course will deal with understanding the molecular basis for the actions of drugs and the characteristics of interactions between drug molecules and those of the substrates of drug action in the cell. This course will be in a seminar format as well as computer based practical programs.
This course is designed to teach graduate students general principles of drug actions in the biological systems. The topics are designed to cover most of the major biological mechanisms involved in drug actions. There will also be opportunity to understand current approaches to the principles that dictate interactions of drugs with biological systems.
This course is devoted to exploring the biosynthesis, inactivation, receptors, and signaling mechanisms of neurotransmitters and chemical mediators including GABA, glutamate, acetylcholine, catecholamines, purines, peptides, prostaglandins, and histamines. In brief, the molecular and cellular aspects of receptor mechanisms as well as signaling pathways, and effector systems will be discussed. The teaching format includes Seminars and discussions.
This course is designed to teach graduate students the mechanisms involved in the actions of drugs and toxins on the target organs. The course will focus on molecular mechanism of chemically-induced toxicity to specific organs in the mammalian species. It describes the principles of cellular and molecular mechanisms of organ system toxicology with emphasis on developmental toxicology, carcinogenesis, immune toxicity, renal toxicity, hepatic toxicity and neurotoxicity.The effects of toxins on respiratory, blood, cardiac, skin and eyes at the cellular level will also be addressed in this course. Various factors affecting toxicity to each particular organ will be studied.
Pharmacy Economic Management provides an overview of the role of economic evaluation in health care with a special emphasis on pharmacy- related issues. Topics include the need for economic evaluation in health care, types of health economic evaluation, and health outcomes measurement and assessment. Leadership concepts will also be studied. This course will incorporate seminars, readings, case exercises and guided discussions to accomplish these goals and will utilize different learning techniques. This course will help students understand what sources of information are appropriate to use in a variety of situations. It uses examples to help students learn to use the Internet to obtain drug information and determine the strengths and weaknesses of various types of drug information.
This course combines the theoretical and case-based approaches to teaching students how to manage drug therapy from a kinetic point of view. Students will evaluate variability in pharmacokinetics due to physiological as well as pathophysiological conditions. They will also learn to approach dosage determinations based upon kinetic properties (i.e. low or high extraction ratio of hepatically cleared drugs, renally cleared and mixed renally-hepatically cleared drugs). Students will, also, be given the opportunity to practice dosing of the selected drugs using a case-study scenario.
This course focuses on the pharmacotherapy in disease management. It covers Infectious Diseases, Multiple Sclerosis Alzheimer's disease, Parkinson's disease, Seizure Disorders, Depression, anxiety Disorders and personality disorders. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to for appropriate care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, and assignments, interactive Internet-based lectures and case studies.
This course focuses on the pharmacotherapy in disease state management of Hypertension, Ischemic Heart Disease, Myocardial Infarct, Heart Failure, Stroke, Anticoagulation, Upper GI Disorders, Asthma & COPD, and Renal Diseases. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, and assignments, interactive Internet-based lectures and case studies.
This course focuses on the pharmacotherapy and the management of diseases and conditions including Hormone Replacement, Osteoporosis, Rheumatoid and Osteoarthritis, Lipid Disorders and Diabetes. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, assignments, interactive Internet-based lectures and case studies.
This course focuses on the pharmacotherapy and the role of the pharmacist in disease state management of diseases and conditions including Cancer, Critical Care and Infectious Diseases. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, assignments, interactive Internet-based lectures and case studies.
The Poisoning & Drug Toxicity course deals with the understanding of general management strategies of poisoning and drug toxicity cases. Furthermore, this course gives an introduction to studying medicines, drugs and poisons. The course considers legal and illegal medicines and drugs used in society, toxic substances in the workplace, environment and homes, and venoms and toxins.
The pharmaceutical care practice rotation is a four-week required rotation for Pharm-D students. The focus of this rotation is the provision of medication related care for the purpose of achieving definite outcomes that improve patient’s quality of life.
The Ambulatory Care rotation is a four-week required rotation. This rotation provides provision of pharmaceutical care for patients seen in Tawam Hospital polyclinic including but not limited to the Anticoagulation, Diabetes, Cardiology and Nephrology Clinics. These ambulatory care services provide chronic disease management and patient/caregiver education including initiation of therapy, drug therapy monitoring and medication adjustment for diagnosed and treated patients referred by their primary care physician.
The General Internal Medicine rotation is a four-week required rotation which allows the provision of evidence-based patient-centered care to patients admitted to the Adult Internal Medicine Service at Tawam Hospital. The Pharm-D students are expected to join the daily multidisciplinary rounds with the medical teaching unit, focusing on management of drug therapy in patients with multiple medical problems.
The Drug Information (DI) rotation is a four-week required rotation in the Drug Information Service. DI under medication management and use is responsible for providing comprehensive, unbiased, evidenced-based medication information; coordination of the activities of the Pharmacy and Therapeutics Committee (PTC); coordination of the medication use evaluation program and other quality improvement initiatives. Additional activities of the DI include management of the hospital formulary system and non-formulary process, development of departmental/hospital policies/protocols to standardize practices and improve overall safety of the medication use process, education of staff regarding medication use policy guidelines and formulary changes through publications, written communications and presentations. A general overview of basic elements in clinical research and good clinical practice will be covered.
The Adult Oncology is a four-week elective rotation. Oncology patients are admitted in to the Oncology/Hematology. The Adult Medical Oncology/Hematology Service in Tawam Hospital is divided into two units. 1. Students are expected to join the medical oncology service multidisciplinary rounds each morning 9-11 AM, Sunday-Thursday. At any given time, the majority of patients are hospitalized for complications of their treatment regimens and/or disease. 2. The rest are hospitalized for chemotherapy and/or radiation. Commonly encountered solid tumors are breast, colon, lung, head and neck, and ovarian cancer. Commonly encountered supportive care issues include pain, nausea/vomiting, bone metastasis and neutropenic fever. Students on rotation will have the opportunity to work with a multidisciplinary team to care for patients with oncologic disorders and related emergencies.
The Pediatric oncology rotation is a four-week elective rotation. Pharm-D students on rotation will have the opportunity to work with a multidisciplinary team to care for pediatric patients with hematologic disorders, oncologic emergencies, acute complications related to cancer, acute leukemia, aggressive lymphomas, and solid tumors requiring complicated or aggressive chemotherapy regimens.
Infectious Diseases is a four-week elective rotation that focuses on the provision of pharmaceutical care to patients seen by the Adult In-patient Infectious Diseases (ID) Service. Patients therefore span all services, in-patient locations, and levels of acuity. The Pharm D student will be responsible for assessing the appropriateness of each patient's medical therapy, designing and modifying therapeutic regimens, and identifying and maintaining therapeutic goals.
This course will provide students the chance to rotate through the laboratory of a potential supervisor to learn about the various projects in progress in that laboratory with emphasis on acquainting themselves with the type of research work and techniques being used. Regular attendance (one hour per week) and active participation of the student in observing and learning about these projects is of great importance. The students should study the literature provided by their respective supervisors and familiarize themselves with the research activities being carried out in the laboratory chosen by them.
The General Pediatrics rotation is a four-week required rotation that focuses on the provision of complete pharmaceutical care services to the pediatric patient population admitted to the general medical unit. The pediatric general medical unit is a 36-bed unit. The patients range in age from newborns to young adults. In addition to general medical cases, other admissions include transfers from PICU and NICU. The student must assume responsibility and accountability for all pharmacotherapy management issues for their assigned patients.
The critical care rotation is a four-week required rotation allowing the provision of pharmaceutical care to a complex critically ill adult, pediatric and neonatal patient population. The adult and pediatric intensive care (PICU) units are 20-bed and 6-bed medical / surgical / cardiac and oncology tertiary care units, respectively. The neonatal intensive care unit (NICU) is a 35-bed unit; patients include both premature infants and term babies with underlying disease. Exposure to a variety of disease states and pharmacotherapy management experience occurs during the rotation. The PICU / NICU are also capable of providing many new and investigational therapies. The student must assume responsibility and accountability for all pharmacotherapy management issues for their assigned patients.
The Emergency Medicine Rotation is a four-week, elective, experientially oriented rotation where the student will be exposed to a broad representation of medical and surgical cases encountered in an emergency department. The focus of experience will emphasize knowledge of evaluation skills and methods for screening the emergencies. There will be a special focus on obtaining relevant history, especially medication history, and performing medication reconciliation. The rotation will provide the student with opportunities to observe the application of special skills in the emergency setting (e.g. interpretation of electrocardiograms, x-rays, CPR and other resuscitation techniques). A major goal of this experience is involvement in pharmacokinetic drug dosing, management of poisoning and drug overdose, as well as the provision of drug information to the multidisciplinary healthcare team on therapeutic/pharmacological intervention. Students are expected to collaborate with emergency physicians, emergency nurses, and other healthcare professionals to promote medication use in the Emergency Department that is evidence-based. Additionally, they will have the opportunity to practice their patient education skills through educating patients and their caregivers about safe and effective medication use.
This course involves independent work on a design, simulation, modeling, development or experiments-related research project. All projects must be supervised by a faculty member involved in mentoring the clinical rotation courses and the student is responsible for finding his/her supervisor. Project topics may be faculty initiated, student initiated, or suggested by industrial contacts. The student is expected to submit a brief description of the work plan by the end of the second week of the semester and a comprehensive final written project by the last week of the semester.
A broad variety of medicinal chemistry approaches can be used for the identification of hits, generation of leads, as well as to accelerate the development of high quality drug candidates. Structure-based drug design (SBDD) methods are becoming increasingly powerful, versatile and more widely used. This course demonstrates current developments in structure-based virtual screening and receptor-based pharmacophores, highlighting achievements as well as pharmacodynamics and pharmacokinetic challenges, along with the value of structure-based lead optimization, with emphasis on recent examples of successful applications for the identification of novel active compounds.
The Surgery rotation is a four-week, elective, experientially oriented rotation where the PharmD student will be exposed to medication management in the surgical care setting. This will include but will not be limited to peri-operative medication management, antimicrobial surgical prophylaxis, deep venous thrombosis prophylaxis and the ordering and monitoring of total parenteral nutrition hospital-wide.
This course is designed to provide students with important skills needed for the provision of drug information in pharmacy practice. Emphasis will be placed on interpretation and critical evaluation of primary medical literature in order to make patient-speciﬁc recommendations. Formulary management, clinical practice guidelines, and mechanisms for evaluating and reporting adverse drug events will also be reviewed. This course will enhance both verbal and written communication skills through multiple small group discussions and several written assignments, including the preparation of a drug formulary monograph.
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